Performance Backed by Peer-Reviewed Science

A study published in the *American Journal of Infection Control (AJIC)* demonstrates a significant reduction in MRSA, fungi, and aerobic bacteria on air and surface bio-burdens, along with over a 70% decrease in healthcare-associated infections (HAIs).

Sustained Reduction in HAIs of 70%+ (CAUTI, CLABSI, C. diff, MRSA)

A significant decline in the total aggregate counts of healthcare-associated infections (HAIs)—including CAUTI, CLABSI, *C. difficile*, MRSA bacteremia, and pneumonia—was observed in both ICUs. At the Louisiana site, a 71% reduction was noted (from 24 HAIs to 7 HAIs) when compared to data from 21 months before AP activation (Fig. A). Similarly, the Kentucky site showed a 70% reduction (from 10 HAIs to 3 HAIs) compared to data from 12 months prior (Fig. B).

Fig. Aggregate counts of surveilled HAIs comparing matched time periods before and after ActiveClean® technology activation for Louisiana (A) and Kentucky (B). CAUTI, catheter-associated urinary tract infection; C difficile, Clostridioides difficile; CLABSI, central line-associated bloodstream infection; MRSA, methicillin-resistant Staphylococcus aureus.

Statistically Significant Reductions in Microbial Reservoirs Across the Environment of Care

Environmental Surface Fungal CFU Reduction

The mean fungal colony-forming units (CFUs) were reduced by 99% at the Louisiana site and 98% at the Kentucky site from baseline to post-activation.

Environmental Floor Fungal CFU Reduction

At the Louisiana site, mean aerobic bacterial colony-forming units (CFUs) decreased by 72% (from 27.3 CFUs to 7.7 CFUs), while mean fungal CFUs saw an 89% reduction (from 10.6 CFUs to 1.18 CFUs) from baseline to post-activation. In contrast, at the Kentucky site, mean aerobic bacterial CFUs increased by 6% (from 9.29 CFUs to 9.86 CFUs), and mean fungal CFUs were reduced by 27% (from 1.57 CFUs to 1.14 CFUs).

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Environmental Air Bacterial and Fungal CFU Reduction

Mean aerobic bacterial and fungal CFUs were reduced by 72% (27.3 CFUs to 7.7 CFUs) and 89% (10.6 CFUs to 1.18 CFUs), respectively, from baseline to postactivation at Louisiana site. Mean aerobic bacterial CFUs increased by 6% (9.29 CFUs to 9.86 CFUs)1 and mean fungal CFUs were reduced by 27% (1.57 CFUs to 1.14 CFUs) at the Kentucky site.

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Surface MRSA CFU Reduction

Mean MRSA colony-forming units (CFUs) were reduced by over 99% at both locations. The Louisiana facility experienced a decrease from 426.98 CFUs to 3.00 CFUs, while the Kentucky facility saw a reduction from 173.61 CFUs to 0.64 CFUs.

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* Illustrated findings were statistically significant.

1 Mean aerobic bacterial air CFUs at the Kentucky site were the only study result to show an increase compared to baseline, which is likely due to the turbulent nature of airflow and ensuing variability of airborne microbe dispersal.